Pheochromocytomas are catecholamine producing tumors of adrenal gland generally diagnosed by presence of these markers in urine or plasma.However, a few may be marker-negative and challenging for clinicians.Several reports of these marker-negative pheochromocytomas may warrant necessity for marvos t coils a new classification of these tumors.
Adrenergic blockade before surgery is one of the main mama mellace s mores reasons for recognition of these cases.We present a case of marker-negative pheochromocytoma which turned out to be malignant on its recurrence.To our knowledge, this is the only case of malignant marker-negative pheochromocytoma reported in literature so far.
Keywords: Pheochromocytoma, Adrenal, Catecholamines, Hypertension.